Unveiling LOX-1 receptor interplay with nanotopography: mechanotransduction and atherosclerosis onset
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چکیده
منابع مشابه
Unveiling LOX-1 receptor interplay with nanotopography: mechanotransduction and atherosclerosis onset
Lectin-like ox-LDL receptors (LOX-1) play a crucial role in the ox-LDL-induced pathological transformation of vessel-wall components, a crucial early step in atherogenesis. LOX-1 dynamics is quantitatively investigated in human endothelial cells (HUVECs) exposed to environmental nanotopographies. We demonstrate distinct nanotopography-induced cell phenotypes, characterized by different morpholo...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2013
ISSN: 2045-2322
DOI: 10.1038/srep01141